J Dermatol. Inhibitory effects of Alpinia speciosa K. SCHUM on the porphyrin photooxidative reaction. It is thought that the beta-carotene defense mechanism against photosensitivity involves the inhibition of singlet oxygen formation, a kind of active oxygen.

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Rangan, Email: moc. Corresponding author. Received May 4; Accepted Aug Open Access. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author s and the source are credited.

This article has been cited by other articles in PMC. Abstract Since prehistoric era, plant-derived drugs were much preferred due to their less side effects than drugs of synthetic origin. Bioassay-guided selection of active fraction of a plant extract and further isolation and characterization of the pure bioactive compounds are in practice in both academic and industrial research.

Zingiberaceae, a medicinally important, ornamental, monocotyledonous family has potential members in the tribe Alpinieae, among which the genus Alpinia is studied under this current review due to its wide range of biomedical applications. The members in the genus possess many bioactive compounds against harmful microbes to deadly diseases like cancer by regulating the different signalling pathway systems.

Several compounds have been discovered and found to deliver diversified biological efficacy either in vitro or in vivo against a range of diseases. The chemical profiling of the genus and investigation of crude essential oils and individual bioactive compounds towards the therapeutic importance in various disciplines have been documented in the current review.

Keywords: Alpinia, Anticancer, Antioxidant, Bioactive compounds, Essential oil, Pharmacological Introduction Plant-derived drug research has become more promising in recent years and also a better alternative for synthetic medicine and therapeutics in spite of many challenges Vanwyk and Wink In spite of great technological advancement in the field of applied science, medical treatments are still in its infancy when the treatment against the deadly diseases like cancer is considered.

In many cases, it has been found that treatment of such diseases with the chemosynthetic drugs shows frequent side effects, toxicity, severe mental and physical abnormalities, not acceptable to the patient and to their families. Nearly, 21, plants have been listed by the World Health Organization WHO , which are in use for diverse medicinal purposes around the world. Being the largest producer of medicinal herbs, India is known as the botanical garden of the world catering to the needs for herbal medicines Seth and Sharma Ethnopharmacogological knowledge towards the scientific investigation of medicinally important plants augments the prospects of alternative medicine and therapeutic values.

The ethnomedical practices of the tribal communities of North East India were critically studied and documented for the Zingiberaceae family towards their future pharmacological diagnostics Tushar et al. This important family is distributed worldwide with about 50 genera and 1, diverse species mainly concentrating in South and Southeast Asia Wu and Larson In India, about 22 genera and species have been reported from North Eastern and peninsular region Jain and Prakash , whereas North East region alone harbours 19 genera and close to about 88 diverse species Prakash and Mehrotra Latin and species description in many cases are in doubtful identity.

The largest genus of the family Zingiberaceae, Alpinia, was classified by Charles Plumier, the famous French botanist and named after Prospero Alpino, the well-known Italian botanist of sixteenth century. The genus includes — species distributed throughout tropical and subtropical climates of Asia and the Pacific. DNA-based studies showed the genus as polyphyletic represented by six clades scattered across the tribe Alpinieae Kress et al. Majority of the members of the genus produces attractive inflorescence, possesses aromatic aerial and underground parts generally subjected to different fractionation process for the extraction of essential oils, aqueous extract and bioactive components.

Various parts of this plant have significant potential to yield bioactive components towards the development of future therapeutics Fig. The essential oil extracted from different parts of the plant contains diverse natural compounds having multiple medicinal properties. Because of its multipurpose utility, the genus Alpinia demands much attention from the researchers towards the development of potential therapeutics against various diseases like cancer, diabetes, ulcer and many neural disorders.

Several research and reviews shows the importance and medical application of potential bioactive compounds isolated from different species of the genus and further research is continuing to unveil the mechanism of action of the natural bioactive compounds in regulating the disease progression and cure.

The current aim of this study is to highlight the exhaustive pharmacological information and promising therapeutic uses of the genus Alpinia.





Alpínia – Origem, Benefícios e como Usar



Inhibitory effects of Alpinia speciosa K. SCHUM on the porphyrin photooxidative reaction.


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